Natural Product Chemistry
Some of the most important medicines in use today began as molecules made by living organisms. Inspired by resilient species such as the agave, we study natural chemistry as a source of structurally novel starting points that synthetic libraries rarely produce on their own.
Bioactive compound discovery
We survey plants, fungi, and microbes that survive extreme conditions, looking for the metabolites they produce to defend themselves and evaluating those molecules for therapeutic potential.
Isolation and structural characterization
Promising extracts are fractionated and characterized so that activity can be attributed to a defined molecule rather than to an unresolved mixture.
Semi-synthetic optimization
Natural scaffolds are rarely drug-ready. We modify them to improve potency, stability, and exposure while preserving the chemistry that made them interesting.
Responsible and traceable sourcing
Material sourcing follows benefit-sharing and biodiversity norms, and we favor cultivated or synthetic supply routes over harvesting pressure on wild populations.
How this connects to our other work
Natural scaffolds enter the same pipeline as every other candidate. They are optimized through drug discovery, matched to targets identified in genomics, and evaluated against existing therapies using the modeling described in artificial intelligence in drug refinement.